![]() We will not be liable for any direct, indirect or consequential loss or damage arising under these terms and conditions or in connection with our website, whether arising in tort, contract, or otherwise – including, without limitation, any loss of profit, contracts, business, goodwill, data, income, revenue or anticipated savings. Our liability is limited and excluded to the maximum extent permitted under applicable law. To the maximum extent permitted by applicable law we exclude all representations, warranties and conditions (including, without limitation, the conditions implied by law of satisfactory quality, fitness for purpose and the use of reasonable care and skill). Whilst we endeavour to ensure that the information on this website is correct, we do not warrant its completeness or accuracy nor do we not commit to ensuring that the website remains available or that the material on this website is kept up-to-date. The information on this website is provided free-of-charge, and you acknowledge that it would be unreasonable to hold us liable in respect of this website and the information on this website. (c) You must not edit or otherwise modify any material on the website. (b) You must not reproduce, duplicate, copy, sell, resell, visit, or otherwise exploit our website or material on our website for a commercial purpose, without our express written consent (a) You must not republish material from (including republication on another website), or reproduce or store material from this website in any public or private electronic retrieval system You may view, download for caching purposes only, and print pages from the website, provided that: Subject to the licence below, all our intellectual property rights are reserved. Unless otherwise stated, we or our licensors own the intellectual property rights in the website and material on the website. If you disagree with any part of these terms and conditions, do not use our website. However, it is hard to know how much pure vitamin C or THDA can be thanked.īottom line: a really promising, but not well-proven vitamin C derivative that can be worth a try especially if you like experimenting (but if you like the tried and true, pure vitamin C will be your best bet).These terms and conditions govern your use of by using our website, you accept these terms and conditions in full. The study was a small (10 patients), double-blind experiment, and the formula did show some measurable anti-aging results. The authors theorized that the 10% AA is released slowly from the silicon delivery system and probably stays in the upper layer of the skin to give antioxidant benefits, while THDA penetrates more rapidly and deeply and gives some wrinkle-reducing benefits. We could find Tetrahexyldecyl Ascorbate mentioned only in one published in-vivo study that examined the anti-aging properties of a silicone formula containing 10% AA and 7% THDA. So this all sounds really great, but these are only in-vitro results at this point. Third, THDA seems to have all three magic abilities of pure vitamin C: it gives antioxidant protection from both UVB and UVA rays, it increases collagen synthesis (even more than AA) and it has a skin brightening effect by reducing melanogenesis by more than 80% in human melanoma cell cultures. There is also in-vitro data showing that it converts to AA in the skin. So great in fact, that it surpasses the penetration of pure vitamin C threefold at the same concentration and it penetrates successfully into the deeper layers of the skin (that is usually important to do some anti-aging work). Second, because it's oil-soluble, its skin penetration abilities seem to be great. ![]() First, it is stable (if pH < 5), easy to formulate, and a joy to work with for a cosmetic chemist. With this context in mind let's see what THDA might be able to do. ![]() In addition, vitamin C's three magic properties (antioxidant, collagen booster, skin brightener) are all properly proven in-vivo (on real people), but for the derivatives, it's mostly in-vitro studies or in the case of THDA, it's in-vitro and done by an ingredient supplier. It's a really promising candidate (see below), but while reading all the goodness about it in a minute, do not forget that derivatives not only have to be absorbed into the skin but also have to be converted to pure vitamin C (ascorbic acid or AA) and the efficacy of the conversion is often unknown. ![]()
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